Neurotoxicity following Lithium and Carbamazepine Interaction - a Case Report
نویسندگان
چکیده
Lithium is now a widely used drug in psychiatry and is the most preferred agent in the prophylaxis of affective disorder. However, about 30-40% of patients do not respond to Lithium. Addition of carbamazepine may be helpful in such cases, where it acts synergistically with Lithium (Forrest 1982, Lipinski et al 1982, Desai et al 1983). We also tried this combination in a case of affective disorder was not responding to Lithium. The patient developed some neurotoxic features, hence the combination had to be withdrawn.
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